Imagine an AI creating a life-saving drug, only to be told it can't be the inventor. The U.S. Patent Office has firmly declared that only humans can be named inventors on patents. In a major reversal, the USPTO scrapped its prior AI-specific guidelines, reinforcing that the legal standard for inventorship remains exclusively human-centric, regardless of the tools used. Even if an AI generates the core of a breakthrough, credit goes to the person who conceived the idea, making the AI legally equivalent to a highly advanced lab instrument. This decision solidifies human oversight in innovation and sidesteps a legal minefield over machine rights and ownership. For now, a drug discovery firm using AI to find new compounds or an engineer using AI to design a jet engine will see their human teams, not their software, listed on the patent.